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Pituitary Cancer

Research from University of Louisville provide new insights into pituitary cancer

Published in Women's Health Law Weekly, September 2nd, 2007

A report, "Development of cystic glandular hyperplasia of the endometrium in Mullerian inhibitory substance type II receptor-pituitary tumor transforming gene transgenic mice," is newly published data in Journal of Endocrinology. According to a study from the United States, "The pituitary tumor transforming gene (PTTG)/securin is an oncogene that is involved in cell cycle regulation and sister chromatid separation. PTTG is highly expressed in various tumors including ovarian tumors, suggesting that PTTG may play a role in ovarian tumorigenesis."

"Overexpression of PTTG resulted in induction of cellular transformation in vitro and tumor formation in nude mice. To...

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