A report, "Development of cystic glandular hyperplasia of the endometrium in Mullerian inhibitory substance type II receptor-pituitary tumor transforming genetransgenic mice," is newly published data in Journal of Endocrinology. According to a study from the United States, "The pituitary tumor transforming gene (PTTG)/securin is an oncogene that is involved in cell cycle regulation and sister chromatid separation. PTTG is highly expressed in various tumors including ovarian tumors, suggesting that PTTG may play a role in ovarian tumorigenesis."
"Overexpression of PTTG resulted in induction of cellular transformationin vitro and tumor formation in nude mice. To...
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