Breast Cancer Genetics
Reports summarize breast cancer genetics research from University of Arizona, Department of Nutritional Sciences
Published in Women's Health Law Weekly, June 22nd, 2008
Current study results from the report, 'Involvement of a specificity proteins-binding element in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene,' have been published. According to recent research from the United States, "Increased estrogen level has been regarded to be a risk factor for breast cancer. However, estrogen has also been shown to induce the expression of the tumor suppressor gene, BRCA1."
"Upregulation of BRCA1 is thought to be a feedback mechanism for controlling DNA repair in proliferating cells. Estrogens enhance transcription of target genes by stimulating the association of the estrogen receptor (ER) and related...
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