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Vascular Endothelial Growth Factor

Studies from University of Texas yield new information about vascular endothelial growth factor

Published in Women's Health Law Weekly, August 30th, 2009

According to recent research from the United States, "Angiogenesis is a hallmark of malignant transformation, With improved understanding of angiogenic signaling in both the normal and malignant state, there have been a number of agents developed that target VEGF signaling, These targeted agents can affect downstream VEGF signal transduction via unique mechanisms at different cellular and extracellular locations."

"The aflibercept, or VEGF-Trap, molecule is the subject of this article, Its molecular structure, pharmacokinetic and pharmacodynamic profile, and preclinical and early clinical data in epithelial ovarian carcinoma is reviewed. For comparison, other...

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