HIV Transmission - Obstetrics

AZT-Resistant HIV Causes Perinatal Transmission

Published in Women's Health Weekly, June 26th, 1995

A Washington state study adds to the evidence that maternal treatment with oral zidovudine reduces the rate of HIV-1 transmission to the baby, but indicates that vertical transmission of virus resistant to zidovudine can occur.

Infection of children with HIV-1 is mostly due to vertical transmission of the virus from an infected mother to her infant in utero, during birth, or by breast-feeding. The rate of perinatal transmission of HIV-1 in the United States has been found to vary between 12 percent and 40 percent.

In a widely reported study, Conner et al. found that the rate of vertical transmission was reduced from 26 percent among placebo-treated...

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Source: Women's Health Weekly (1995-06-26)

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