Published in Women's Health Weekly, September 4th, 1995
uPA is a protease involved in the process of cell migration and tissue remodelling. It has been found in the ascitic fluid of advanced ovarian cancer patients. It is not found in non-malignant ascitic fluid (i.e., from liver cirrhosis). Prospective clinical studies have shown that the presence of uPA in cancerous tissue extracts was a strong prognostic indicator for relapse-free and overall survival of patients with ovarian, breast or gastric...
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