Women's Health Weekly
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Contraceptives - Vaccine
Oral Immunization Considered Effective with Recombinant Product
September 11th, 1995
Induction of sperm-specific antibodies in the reproductive tract following oral administration of a recombinant Salmonella could lead to the development of a simple, safe, efficient, and easy-to-use contraceptive vaccine. Several gamete-specific antigens that are involved in sperm-egg interaction have been identified, including the sperm-specific antigen SP10. SP10 is a human sperm acrosomal antigen that has been designated a primary vaccine candidate by a World Health Organization (WHO) task force on contraceptive vaccines (Anderson et al., Canada J Reprod Immunol 1987;10:231-257). Human SP10 exists in the acrosome and can be detected as a series of...
Source: Women's Health Weekly (1995-09-11)
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