AIDS/HIV (Transmission)

AZT Resistance and Mother-to-Child Transmission

Published in Women's Health Weekly, October 2nd, 1995

In findings that bear directly on the question of how to prevent mother-to-child transmission of HIV, scientists have shown that virus resistant to the most widely used AIDS drug, AZT, may arise in HIV infected pregnant women and be transmitted to their infants.

These results suggested that to monitor the efficacy of AZT therapy during pregnancy, it may be necessary to measure both the amount of HIV in the mother, which has been shown previously to be a major determinant of transmission, and whether resistance to AZT is present. They also demonstrated that AZT therapy alone may not be effective in preventing transmission from some women; in these pregnant women,...

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Source: Women's Health Weekly (1995-10-02)

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