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Cancer (Genetics)

BRCA2 Gene Linked to Several Types of Cancer

Published in Women's Health Weekly, May 6th, 1996

Evidence mounts that BRCA2, the second, remarkably large breast cancer gene, is also linked to a number of other types of cancer.

Researchers report the findings in four papers published in the May 1996 issue of Nature Genetics (1996; 120-121,122-123,123-125,126-129).

Researchers have now identified two specific deletions on BRCA2 that lead to breast cancers. Frameshift mutations in BRCA2 are linked to male breast cancers and pancreatic cancers.

Researchers at Memorial Sloan-Kettering, the University of Utah and Myriad Genetics, Inc. of Salt Lake City, led by Dr. Kenneth Offit, found a high rate of a deletion mutation in BRCA2...

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