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Obstetrics (AIDS/HIV-Vertical Transmission)

Fetal Membrane Rupture Linked to Increased Risk

Published in Women's Health Weekly, July 8th, 1996

"The risk of transmission of HIV-1 from mother to infant increases when the fetal membranes rupture more than four hours before delivery," according to a report in the June 20, 1996, issue of The New England Journal of Medicine (NEJM 1996;334:1617-1623,1664-1665).

In an effort to identify obstetrical factors associated with increased risk of HIV-1 transmission, Dr. Sheldon H. Landesman, State University of New York (SUNY) in Brooklyn and his colleagues evaluated 525 HIV positive women enrolled in the Women and Infants Transmission Study. He followed the women and their infants for three years following delivery.

Landesman found that 25 percent of...

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