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Hypercholesterolaemia (Therapy)

Differences in the Response of Serum Lipoproteins to Fenofibrate Between Women and Men with Primary Hypercholesterolaemia

Published in Women's Health Weekly, August 19th, 1996

According to the authors' abstract of an article published in European Journal of Clinical Pharmacology, "Objective: We studied possible sex differences of the effect of fenofibrate on serum lipoproteins. Twenty-three patients with primary hypercholesterolaemia (10 postmenopausal women and 13 aged-matched men) were treated with slow-release fenofibrate for 96 weeks. Results: Steady state lipoprotein concentrations were reached after 12 and 24 weeks of treatment in women and men, respectively. During the subsequent follow-up the lipoprotein concentrations remained constant. In women total and low-density lipoprotein (LDL) cholesterol decreased from 299 to 234 mg.dl and...

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