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NIH Grants

Spore in Breast Cancer Sub Title Gene Discovery--Protein Kinases in Breast Cancer

Published in Women's Health Weekly, October 28th, 1996

Amount: $173,961 per year. Grant Expires: 4 Fiscal Years. Project Number: 2 P50 CA58223-04 SUB: 0006. Principal Investigator: Edison T. Liu. Performing Organization: University of North Carolina Chapel Hill. Abstract: Protein kinases are regulators of cellular proliferation. Several, e.g. HER-2/neu, and the epidermal growth factor receptor (EGFR), have been implicated in the pathogenesis and progression of human breast cancer. We propose to identify novel protein kinases from human breast carcinomas, and to study, in the clinical setting, those likely to be directly involved in the growth and proliferation of breast cancer cells....

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