Effect of Natural Estrogens on the Vessel Wall - Molecular Mechanisms and Clinical Implications

According to the authors' abstract of an article published in Schweizerische Medizinische Wochenschrift, "Myocardial infarction is the major cause of death in the Western world. Men are more prone to develop coronary artery disease than women, who rarely develop coronary disease before menopause. Although epidemiological data has long been available showing a protective effect of estrogen on the vascular system, the underlying mechanisms have been investigated more thoroughly only in recent years. Meta-analysis studies have revealed that only half of the protective effect on estrogen replacement therapy is due to its positive effects on the lipid profile and that a large part of this...

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