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Breast Cancer (Therapy)

Proven Superiority of High Dose Chemotherapy for Metastatic Disease

Published in Women's Health Weekly, November 25th, 1996

High dose chemotherapy is clinically efficacious for metastatic breast cancer, researchers report.

Despite early diagnosis and improvements in adjuvant therapy, the mortality rate for breast cancer remains high. Currently, some 30 percent of patients who appear to have clinically localized disease will die of metastatic breast cancer. This figure jumps to 70 percent for those patients who have poor prognostic features at diagnosis (e.g., >10 nodes positive). Once the cancer has metastasized, the disease is essentially incurable with conventional treatment protocols.

In an effort to overcome the limitations of conventional treatments, high dose...

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