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Obstetrics (HEV)

Severe Hepatitis E Infection during Pregnancy

Published in Women's Health Weekly, February 17th, 1997

According to the authors' abstract of an article published in Journal of Viral Hepatitis, "In areas with endemic hepatitis E virus (HEV), acute liver failure secondary to hepatitis E infection is common in pregnancy and associated with a mortality rate of up to 20%. However, there is little information on the clinical course of severe hepatitis E infection during pregnancy in non-endemic areas such as the UK. Here we describe two cases of severe hepatitis E in pregnancy in patients returning from the Indian subcontinent. These cases were diagnosed by the detection of IgM anti-HEV antibody using an enzyme immunoassay with recombinant hepatitis E viral antigens. The first case describes...

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