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Lupus (Drug Development)

Results of Phase III Trial of GL701 for Lupus Presented

Published in Women's Health Weekly, May 5th, 1997

Genelabs Technologies, Inc. reports that a treatment response was observed in a group of women with clinically active systemic lupus erythematosus (SLE), which constituted the majority of patients enrolled in the company's first pivotal clinical trial for GL701 (DHEA).

The study, however, did not achieve statistical significance when all patients were included in the analysis, as an unexpectedly high response rate to placebo was observed among those patients with minimal or no disease activity at baseline. This Phase III trial was designed to show whether the use of GL701 in women with SLE would allow reduction in their steroid doses while maintaining stable or reduced...

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