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Osteoporosis

The Response to Calcitriol Therapy in Postmenopausal Osteoporotic Women Is a Function of Initial Calcium Absorptive Status

Published in Women's Health Weekly, July 28th, 1997

According to the authors' abstract of an article published in Calcified Tissue International, "Calcitriol is used in the treatment of osteoporosis but the indications for its use have not been clearly defined. Because it stimulates calcium absorption, we have tended to select osteoporotic patients with low calcium absorption for this therapy and now report the results. We measured the hourly fractional rate of calcium absorption (alpha) with Ca-45 and fasting urinary calcium/creatinine (Ca/Cr) and hydroxyproline/creatinine (OHPr/Cr) in 103 postmenopausal women aged 68 (0.67SE) years with vertebral compression fractures (77) or forearm or vertebral bone density below the young normal...

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