Breast Cancer (Genetics)

Scientists Identify Tumor Suppressor Gene

Published in Women's Health Weekly, August 4th, 1997

Scientists at Oregon Health Sciences University (OHSU) in collaboration with a team from the University of California at Santa Cruz have discovered that abnormal expression of a tumor suppressor gene is implicated in breast cancer.

Their work appears in the July 22, 1997 issue of the Proceedings of the National Academy of Sciences and details the action of a gene called WT1, which had been linked previously to kidney cancer in children.

"The WT1 gene normally prevents cell division by inhibiting the synthesis of growth factors that themselves trigger cell growth," explains Charles T. Roberts, Ph.D., professor of pediatrics at Oregon Health Sciences...

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Source: Women's Health Weekly (1997-08-04)

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