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Breast Cancer (Genetics)

New Gene May Intensify Breast Cancer Growth

Published in Women's Health Weekly, September 1st, 1997

Scientists in the National Human Genome Research Institute (NHGRI) at the National Institutes of Health (NIH) have discovered a new gene that is pivotal to a crucial metabolic pathway linked to the growth and progression of human breast cancer.

The gene appears to be expressed at abnormally high levels in tumor cells of most breast cancer patients, more than half of cases examined so far. The researchers reported their findings in the August 15, 1997 issue of Science.

In many cancers, but especially breast cancer, tumor cells accumulate extra copies of genes that give the cancer a growth advantage. The new gene is one such amplified gene. The...

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