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Hormone Replacement Therapy

Estrogen Quickly Reduces Lipoprotein (a) -- But "How" Remains A Mystery

Published in Women's Health Weekly, September 29th, 1997

Estrogen replacement therapy (ERT), used to help relieve menopausal symptoms, quickly reduces the amount of lipoprotein (a) (Lp (a)) in the blood.

ERT taken orally reduces the amount of Lp (a), a "bad cholesterol," within a week, and the maximum effect was seen after three weeks. The estrogen also increases the amount of high-density lipoprotein (HDL), the so-called "good cholesterol," said researchers at the Columbia University College of Physicians and Surgeons in New York, reporting in the September 1997 issue of the journal Arteriosclerosis, Thrombosis, and Vascular Biology.

The method of reducing this form of cholesterol differs physiologically...

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