Published in Women's Health Weekly, December 22nd, 1997
To investigate the function of P-cadherin in mice, which is only expressed in specialized myoepithelial cells of the mammary gland, researchers created P-cadherin-deficient mice ("P-cadherin knockouts").
"In the P-cadherin knockouts, we found that breast tissue of virgins resembled that of pregnant animals, and as these animals aged, we also saw a hyperproliferation of breast tissue," explains Glenn L. Radice, PhD, assistant...
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