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Irritable Bowel Syndrome (Treatment)

Phase II Trial Data Encouraging for Women

Published in Women's Health Weekly, June 15th, 1998

Results from a Phase II dose ranging trial suggest that the investigational drug alosetron hydrochloride provides adequate relief of pain and discomfort for females with irritable bowel syndrome (IBS).

The results, presented by Allen Mangel, MD, clinical research director, Glaxo Wellcome Inc., during the Digestive Disease Week (DDW) conference in New Orleans, Louisiana, showed that the proportion of female patients who reported adequate relief of IBS-related pain and discomfort was significantly greater with alosetron (1 and 2 mg BID) than the proportion of patients reporting adequate relief with placebo. Female patients taking alosetron also reported improved stool...

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