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Osteoporosis (Therapy)

The Effect of Sodium Monofluorophosphate Plus Calcium on Vertebral Fracture Rate in Postmenopausal Women with Moderate Osteoporosis - A Randomized, Controlled Trial

Published in Women's Health Weekly, August 10th, 1998

According to the authors' abstract of an article published in Annals of Internal Medicine, "Background: Fluoride is effective in increasing trabecular bone mineral density (BMD) in the spine, but its efficacy in reducing vertebral fracture rates and its effect on BMD at cortical sites are controversial. Objective: To study the effect of low-dose fluoride (sodium monofluorophosphate [MFP]) plus a calcium supplement over 4 years on vertebral fractures and BMD at the lumbar spine and total hip in postmenopausal women with moderately low BMD of the spine. Design: Randomized, double-blind, controlled clinical trial. Setting: Outpatient clinic for...

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