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Ovarian Cancer

Progestin May Trigger Death of Damaged Ovarian Cells

Published in Women's Health Weekly, September 14th, 1998

Researchers at Duke University Medical Center in Durham, North Carolina, have reported results from animal studies that may explain for the first time why oral contraceptives offer protection against ovarian cancer.

Their findings suggest that the hormone progestin in birth control pills induces ovarian cells that are damaged to die before they turn malignant.

The discovery offers hope that periodically administering progestin to wipe out precancerous ovarian cells could be a highly effective preventive treatment for ovarian cancer, which kills 17,000 women in the United States annually. The researchers plan to begin human trials of the therapy this...

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