Anticonvulsant Therapy and Bone Mineral Density in Post-Menopausal Women

According to an abstract submitted by the authors to the Annual Meeting of the British Society for Rheumatology, held September 10-11, 1998, in Manchester, England, "Women aged over 65 years receiving anticonvulsant therapy have an almost threefold increased risk of hip fracture compared to healthy women of the same age. This risk remains increased two-fold at the hip independent of bone mineral density (BMD). Children and young adults taking anticonvulsants can have biochemical and histological evidence of osteomalacia with increased fracture risk. These observations suggest that fracture risk in these patients may be influenced by bone mass and by bone quality. We measured serum...

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