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Women's Health Weekly

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NIH Grants (Human Papillomavirus)



Canine Oral Papillomavirus--Model for a Vaccine



September 28th, 1998

Project Number: 5 R01 CA57994-06. Grant Expires: 2 Fiscal Years. Principal Investigator: Schlegel, Richard. Performing Organization: Georgetown University. Abstract: "Papillomaviruses play a critical role in inducing malignant epithelial tumors of the oral and genital tract in humans. In our first grant awarded by the National Cancer Institute, we developed a canine model for evaluating the efficacy of vaccines in preventing infection by a mucosotropic papillomavirus (COPV). Our results indicated that the systemic administration of an L1 capsid protein vaccine was completely effective in preventing oral tumors. In addition, the studies...


Source: Women's Health Weekly (1998-09-28)

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