Women's Health Weekly
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Dermatology
Spironolactone is Effective Treatment for Acne in Women
September 28th, 1998
Spironolactone effectively treated acne resulting from excessive androgen production in women with this condition. Spironolactone, 50 mg taken twice daily on days 5-21 of the menstrual cycle, reduced severity of acne in 32 of 38 women (97 percent), with the most common side effect being metrorrhagia (irregular bleeding between periods), reported Hanna G. Lubbos, MD, and her colleagues in Philadelphia, Pennsylvania, in the September 1998 issue of the Archives of Dermatology ("Adverse Effects of Spironolactone Therapy in Women With Acne," Arch Dermatol, Sept 1998;134;Vignettes:1162-63). The drug's mechanism of action includes interference with androgen...
Source: Women's Health Weekly (1998-09-28)
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