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Women's Health Weekly

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Autoimmune Diseases (Lupus/RA)



Marker of Autoimmune Disease Activity Identified



September 28th, 1998

University of Texas Southwestern Medical Center at Dallas researchers have uncovered what they believe is a marker of autoimmune disease activity in patients with lupus and rheumatoid arthritis. It may one day enable doctors and patients to predict disease flare-ups.

In the September 15, 1998, issue of the Journal of Clinical Investigation, Dr. Mark Siegelman, associate professor of pathology at UT Southwestern, and colleagues described the correlation of disease flare-ups in pediatric patients with lupus and rheumatoid arthritis with the level of activated CD44 (the marker) in circulating blood. The activated form of CD44, a cell surface molecule induced on a small...


Source: Women's Health Weekly (1998-09-28)

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