Hormone Replacement Therapy
Estradiol Therapy Combined with Progesterone and Endothelium-Dependent Vasodilation in Post-menopausal Women
Published in Women's Health Weekly, October 19th, 1998
According to the authors' abstract of an article published in Circulation, "Background: Epidemiological studies indicate that estrogen replacement therapy decreases the risk of cardiovascular events in post-menopausal women. Estrogen may confer cardiovascular protection by improving endothelial function because it increases endothelium-dependent vasodilation. It is not known whether progesterone attenuates the beneficial effects of estrogen on endothelial function. Methods and Design: Seventeen post-menopausal women with mild hypercholesterolemia were enrolled in a placebo-controlled, crossover trial to evaluate the effect of transdermal estradiol, with and without...
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