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Hormone Replacement Therapy

Fibrinolytic Potential Is Significantly Increased by Oestrogen Treatment in Post-Menopausal Women with Mild Dyslipidaemia

Published in Women's Health Weekly, October 19th, 1998

According to the authors' abstract of an article published in Heart, "Objective: To study the effects of oestrogen replacement treatment on fibrinolytic potential in post-menopausal women. Designs: Randomised, double-blind, placebo-controlled trial of oral 17 beta-oestradiol. Setting: Subjects were evaluated in the outpatient setting. Patients: Nineteen post-menopausal women with mild dyslipidaemia, aged 44 to 69 years (mean (SD) 55.7 (6.7)). Main Outcome Measures: Fibrinolytic activity (fibrin plate assay) and tissue plasminogen activator (t-PA) antigen were measured at baseline and after three, six, and nine weeks of each treatment. ...

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