Breast Cancer (Drug Resistance)

Discovery May Help Overcome Resistance to Tamoxifen

Published in Women's Health Weekly, January 11th, 1999

Vanderbilt Cancer Center, Nashville, Tennessee, researchers have reported a discovery that could help overcome a major obstacle in treating breast cancer with tamoxifen -- the resistance that breast tumor cells commonly develop to this "anti-estrogen" drug.

Writing in the January 6, 1999, issue of the Journal of the National Cancer Institute, the researchers reported that overproduction of a certain growth factor, called TGF-beta, contributes to tamoxifen resistance. They also demonstrated that the immune system's natural killer activity is important for tamoxifen's anti-cancer effects.

Ultimately, both findings might be exploited to keep tumors...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Women's Health Weekly

Source: Women's Health Weekly (1999-01-11)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry