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Breast Cancer (Therapy)

Patients Might be Candidates for Peptide Immunotherapy

Published in Women's Health Weekly, January 11th, 1999

Breast cancer patients with HLA-A26 or -A24 haplotype might be candidates for specific immunotherapy with SART-1 peptides.

M. Kawamoto and colleagues from the Kurume University School of Medicine, Japan, investigated in breast cancers the expression of the SART-1 gene encoding tumor rejection antigens ("Expression of the SART-1 Tumor Rejection Antigen in Breast Cancer," International Journal of Cancer, January 5, 1999;80(1):64-67).

"SART-I mRNA was expressed in all of the samples tested," wrote Kawamoto et al. "The SART-I-800 antigen was detectable in 20 of 50 (40 percent) breast cancer tissues and all breast cancer cell lines tested, but not in...

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