Breast Cancer

Breast Density, Hormone Replacement, and Cancer Risk

Published in Women's Health Weekly, March 1st, 1999

Research has shown that women age 45 or older who have at least 75 percent dense tissue on a mammogram are at an elevated risk of developing breast cancer. Reasons for this are not completely understood.

Studies, including recently published data from the Postmenopausal Estrogen/Progestin Interventions (PEPI) trial, show that about one-quarter of women who use hormone replacement therapies (HRT) that include progestin have an increase in breast density on their mammograms. In PEPI, a smaller proportion (about 8 percent) of women taking estrogen-only therapies also had increased breast density. However, it is not known if increased breast density due to HRT carries...

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Source: Women's Health Weekly (1999-03-01)

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