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Alloimmunization

Male Fetuses Require Intense Antepartum Surveillance

Published in Women's Health Weekly, March 15th, 1999

Male fetuses are affected more severely by maternal alloimmunization to D antigen than female fetuses, researchers report.

Barbara Ulm and colleagues from Austria's University Hospital of Vienna presented data from all pregnancies referred in the last six years to their prenatal unit for fetomaternal alloimmunization to D antigen ("Male Fetuses Are Particularly affected by Maternal Alloimmunization to D antigen," Transfusion, February 1999;39(2):169-173).

The research group previously hypothesized that male fetuses will be affected more severely by maternal red cell (RBC) alloimmunization than female fetuses (Ulm et al., [letter], N Engl J Med,...

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