Breast Cancer (AACR Conference News)

Further Proof of Damage to the FHIT Gene in Breast Cancers Found

Published in Women's Health Weekly, April 26th, 1999

Scientists at Thomas Jefferson University in Philadelphia, Pennsylvania; the University Hospital of Iceland in Reykjavik; and the National Human Genome Research Institute in Bethesda, Maryland, have found further evidence linking damage to the tumor suppressor gene FHIT to the development of breast cancer.

In a study of 92 Icelandic women, the researchers, led by Kay Huebner, PhD, professor of microbiology and immunology at Jefferson Medical College and a member of Jefferson's Kimmel Cancer Center, showed reduced levels of Fhit, the protein for which FHIT encodes, both in women with sporadic breast cancer and those with hereditary breast cancer who carry a BRCA2...

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Source: Women's Health Weekly (1999-04-26)

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