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Lupus (Animal Models)

Key Peptides Found that Stop - Even Reverse - Kidney Disease in Lupus Patients

Published in Women's Health Weekly, May 17th, 1999

Northwestern University Medical School (Chicago, Illinois) researchers have identified key peptides - small bits of proteins - that halt kidney disease in lupus, an autoimmune disease that attacks the body's own DNA.

In an article in the May 15, 1999, issue of the Journal of Immunology, Syamal Datta, MD, the Solovy Arthritis Research Society Professor, and colleagues at Northwestern reported that brief therapy with the peptides in young, lupus-prone mice markedly delayed the onset of severe, lupus-related kidney disease. Long-term therapy with the peptides in adult mice with established kidney disease prolonged survival and even stopped progression of their disease....

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