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Combination Therapy Well Tolerated in Ovarian Cancer Patients

Published in Women's Health Weekly, June 14th, 1999

Suicide gene therapy followed by concomitant chemotherapy after debulking surgery for recurrent ovarian cancer was well tolerated and non-toxic to patients.

A. Hasenburg, representing colleagues from the Freiburg University Medical Center, Germany, and the Baylor College of Medicine, Texas, presented data from a Phase I study of adenovirus-mediated herpes simplex virus-thymidine kinase (HSV-TK) suicide gene therapy combined with topotecan chemotherapy and surgery in ovarian cancer patients with recurrent disease at the 35th Annual Meeting of the American Society of Clinical Oncology, held May 15-18, 1999, in Atlanta, Georgia (abstract "Phase I Study of Adenovirus...

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