Breast Cancer (Therapy)
Potential Mechanism Behind Tamoxifen Resistance Identified
Published in Women's Health Weekly, August 9th, 1999
They say their discovery could lead to new drugs that either work better than tamoxifen or prevent a woman's resistance to the drug.
The researchers, from Duke University Medical Center, Durham, North Carolina, and Novalon Pharmaceutical Corp., Research Triangle Park, North Carolina, reported in the July 30, 1999, issue of Science that tamoxifen initiates a cascade of changes inside the breast cell that are far different from the effects of estrogen or other compounds that rouse the estrogen receptor to...
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