"Predictive Value of Human Leukocyte Antigen Class II Typing for the Development of Islet Autoantibodies and Insulin-Dependent Diabetes Postpartum in Women With Gestational Diabetes."

According to the authors' abstract of an article published in Journal of Clinical Endocrinology and Metabolism, "Gestational diabetes mellitus (GDM) is a risk factor for the development of insulin-dependent diabetes mellitus (IDDM) and noninsulin-dependent diabetes mellitus postpartum. To evaluate whether there is any association of human leukocyte antigen (HLA) class II alleles (DR and DQ) with GDM and the postpartum development of IDDM, we analyzed 184 women with GDM from Germany for HLA class II alleles, islet autoantibodies [islet cell autoantibodies (ICA), glutamic acid decarboxylase autoantibodies (GADA), and protein tyrosine phosphatase IA-2 autoantibodies (IA-2A), and the...

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