Breast Cancer (Proteomics)

Cancer Gene Inhibitor Discovered

Published in Women's Health Weekly, September 27th, 1999

Researchers at Oregon Health Sciences University and the Vollum Institute have discovered a naturally-occurring protein that inhibits the functions of the HER-2 oncogene, a major factor in breast and other cancers.

The protein, dubbed herstatin, blocks the HER-2 signaling activity that causes tumor cells to grow, ultimately killing those cells. The findings are reported in the September issue of Proceedings of the National Academy of Sciences.

"This particular gene, HER-2, has such a clear-cut role in breast cancer that if you can inhibit its biochemical activity, you should be able to control the cancer," said Gail Clinton, PhD, associate...

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Source: Women's Health Weekly (1999-09-27)

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