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Heart Disease (Treatment)

Study Suggests Why Estrogen Is Not Helpful Against Heart Disease

Published in Women's Health Weekly, September 27th, 1999

Researchers long believed that post-menopausal women undergoing hormone replacement therapy may also gain an added reduction in their risk of developing coronary artery disease. But when a major study released in 1998 showed no such reduction in risk, cardiologists wondered why.

Now, a new study may reveal part of the reason: the gene that's responsible for making receptors to the hormone estrogen might be 'out of service' as a consequence of atherosclerosis, preventing the formation of the receptor. If there aren't enough of these receptors within the cells making up the arteries of the cardiovascular system, estrogen cannot provide any preventative effect.

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