Endometrial Cancer (Risk Factors)
Defective Gene Linked to Cancer
Published in Women's Health Weekly, November 1st, 1999
Scientists looked in families with a condition called hereditary non-polyposis colorectal cancer, or HNPCC, which is caused by defects in DNA repair genes.
Such families run high rates of endometrial cancer, and defects in two other DNA repair genes have already been linked to that cancer.
The new work found endometrial cancer in some 70 percent of HNPCC family women who inherited mutations in a repair gene called MSH6. The result is reported in the October 1999 issue of Nature Genetics by a team that includes Riccardo...
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