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Lupus (Industry News)

Blood Test Identifies Patients Whose Antibodies Bind Well to Lupus Drug Candidate

Published in Women's Health Weekly, January 22nd, 2000

La Jolla Pharmaceutical Company announced publication of a scientific paper on a blood test used in its recent analysis of data from the Phase II/III clinical trial in lupus patients.

The new blood test measures the strength of the binding between the company's lupus drug candidate, LJP 394, and a patient's antibodies to double-stranded DNA.

In December 1999, the company reported that more than 80% of patients evaluated to date who were enrolled in the trial tested positive by this blood assay. In the Phase II/III clinical trial, for patients tested to date with high-affinity antibodies for LJP 394, 30%, or six out of 20 flares occurred in the drug...

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