Lung Cancer

K-ras Mutations More Frequent in Women, Useful for Prognosis

Published in Women's Health Weekly, February 19th, 2000

K-ras gene mutation is a marker of aggressive non-small-cell lung cancer (NSCLC), especially in women, researchers say.

H. H. Nelson and colleagues at Harvard University examined the occurrence of K-ras mutation NSCLC in order to define patient characteristics associated with K-ras mutation and to find whether K-ras mutation might be a marker of patient prognosis ("Implications and prognostic value of K-ras mutation for early-stage lung cancer in women," Journal of the National Cancer Institute, 1999;91(23):2032-2038).

Nelson et al. examined consecutive, newly diagnosed patients with lung cancer who had been treated with potentially curative...

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Source: Women's Health Weekly (2000-02-19)

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