Fibromyalgia (NIH Grant News)

Project Aims to Develop Animal Model of Fibromyalgia Pain

Published in Women's Health Weekly, February 19th, 2000

The US National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health, is funding a study conducted by Georgetown University researcher Luc Jasmin on a rat model of fibromyalgia pain.

The model presupposes a dysfunction of the noradrenergic system as "a unifying explanation for many seemingly disparate findings in fibromyalgia by accounting for the neuroendocrine and autonomic abnormalities, in addition to the chronic pain," Jasmin said.

"Our guiding hypothesis is that in fibromyalgia, chronically decreased noradrenergic input to the spinal cord facilitates substance P release and subsequent hyperalgesia...

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Source: Women's Health Weekly (2000-02-19)

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