Spontaneous Abortion

Effects of Paternal Lymphocyte Immunization Evaluated in Patients

Published in Women's Health Weekly, April 15th, 2000

The effects of paternal lymphocyte immunization on peripheral Th1/Th2 balance and TCR V beta and V gamma repertoire were evaluated in patients with recurrent spontaneous abortions.

"The mechanism of immunotherapy for patients with recurrent spontaneous abortions is not well understood," stated S. Hayakawa and colleagues in Japan. "In order to investigate the suppressor mechanism of paternal lymphocyte immunization, we examined peripheral blood lymphocyte subpopulations and the repertoire of T-cell receptor (TCR) gene segments."

Hayakawa et al. published the results of their study in American Journal of Reproductive Immunology ("Effects of...

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Source: Women's Health Weekly (2000-04-15)

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