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Women's Health Weekly

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Uterine Endometrial Carcinoma



Association with Expanded Repeat in Human Androgen Receptor Gene Suggested



May 6th, 2000

Expansions of the CAG repeat in the androgen receptor gene could be associated with uterine endometrial carcinoma, according to researchers.

Some studies suggest that receptor-mediated androgens play a role in uterine endometrial carcinoma, while others have found evidence that the CAG repeat in the coding region of exon 1of the human androgen receptor gene may be linked to carcinogenesis, according to researchers.

M. Sasaki, of the University of California at San Francisco, and colleagues studied DNA samples from 29 patients exhibiting sporadic endometrial cancer. The researchers looked for alterations in the alleles of 12 exceedingly...


Source: Women's Health Weekly (2000-05-06)

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