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Leptin Studies

High Leptin Levels Associated with Insulin Resistance among Lean and Obese Women

Published in Women's Health Weekly, June 29th, 2000

Insulin and insulin resistance are linked to increased blood leptin levels independent of a person's body mass index, according to a recent report.

Since leptin levels are proportional to a person's amount of adipose tissue and leptin is derived from insulin, C. Albala and colleagues in Santiago, Chile, hypothesized that insulin might have an independent effect on the regulation of leptin secretion.

They therefore conducted a study of 145 obese and lean women aged 20 to 60 years. The subjects' body weight, height, and waist and hip circumference were measured and fasting blood glucose, insulin, and leptin levels were recorded.

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