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Fibromyalgia

Ketamine Can Reduce Symptom Severity

Published in Women's Health Weekly, July 6th, 2000

The NMDA-antagonist ketamine can significantly reduce pain associated with fibromyalgia syndrome (FMS), according to researchers writing in the journal Pain.

"Central mechanisms related to referred muscle pain and temporal summation of muscular nociceptive activity are facilitated in fibromyalgia syndrome (FMS) patients. The present study assessed the effects of an NMDA-antagonist (ketamine) on these central mechanisms," explained T. Gravennielsen and colleagues at the University of Aalborg in Denmark ("Ketamine reduces muscle pain, temporal summation, and referred pain in fibromyalgia patients," Pain, 2000;85(3):483-491).

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