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Carcinogenesis

Bombesin/Gastric-Releasing Peptide Receptors Seen on Human Ovarian Tumors

Published in Women's Health Weekly, August 24th, 2000

Government researchers at the Veterans Affairs Medical Center in New Orleans, Louisiana, say that special receptors for growth factors that cause cancer can be found on ovarian cancer tumors.

Antagonists against these receptors could be used in treating ovarian cancer, they report in the journal Regulatory Peptides.

B.D. Sun et al. studied three receptors for growth factors known as bombesin/gastrin releasing peptides (GRP) in ovarian tumor specimens and ovarian cancer cells in culture.

"Bombesin-like peptides can function as autocrine or paracrine growth factors and stimulate the growth of various cancers," Sun et al....

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