Cancer Therapies

Mouse Study May Lead to Ways to Preserve Fertility in Women Undergoing Cancer Treatment

Published in Women's Health Weekly, October 26th, 2000

A team of researchers from the Massachusetts General Hospital (MGH), Memorial Sloan-Kettering Cancer Center in New York, and other research centers has found a molecule that, in animal studies, has blocked the destruction of ovarian egg cells (oocytes) by radiation therapy.

The report, in the October 2000 issue of Nature Medicine, describes how a compound called sphingosine-1-phosphate (S1P), which blocks the activity of a cell-death-associated molecule called ceremide, preserved ovarian egg cells and fertility in female mice exposed to levels of radiotherapy that otherwise would have destroyed their ovaries. The researchers expect that the same protection...

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Source: Women's Health Weekly (2000-10-26)

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